Preheat oven to 450 degrees F and grease a 9x13 inch baking dish with cooking spray. Set aside.
Place soup, sour cream, milk, salt, paprika, pepper, garlic powder, and onion powder into a large bowl.
Stir until well combined.
Stir in chopped broccoli, cubed chicken, and 1/2 the cheese.
Pour mixture into prepared baking dish.
Top with remaining cheese. Set aside.
Melt butter and mix with the crushed ritz crackers.
Sprinkle over the chicken mixture.
Bake in preheated oven for 15 minutes, or until heated through and lightly brown.